Moxidectin Injection For Dogs

In a laboratory effectiveness study dogs with 4 and 6 month old heartworm infections administered moxidectin microspheres at a dose of 0 17 mg kg experienced vomiting lethargy and bloody diarrhea.

Moxidectin injection for dogs. His love is unconditional and so is yours. Just 1 shot of proheart 6 from your veterinarian provides your dog with 6 months of protection and gives you 6 months peace of mind. It works similarly to other anthelmintic drugs like ivermectin and milbemycin by interfering with important neurotransmissions in parasites so that they become paralyzed and die. Immitis received either proheart 12 at 1 5 mg kg body weight 3x 8 dogs or a saline injection control 8 dogs.

Moxidectin is available in 30 mcg 68 mcg and 136 mcg tablets. And in case you missed it there s 3 times as much moxidectin in proheart 12 as proheart 6 so side effects are likely to be greater this is the exact list of adverse events on the label. He s your best friend. The recommended dose is 0 5 mg kg subcutaneously once yearly.

The proheart 12 injection works similarly to proheart 6 but instead of providing heartworm protection for six months it will last a whole year. It works by slowly releasing microspheres of the antiparasitic drug moxidectin over the course of 12 months. Zoetis knows moxidectin can be harmful to dogs. 10 moxidectin in glyceryl tristearate microspheres was evaluated in four studies using beagle dogs and one study using ivermectin sensitive collies.

At 119 days post infection 56 days post moxidectin treatment no adverse clinical signs and no gross pathological effects were. Safety margin was evaluated as 3 treatments of ph 12 0 control. In a laboratory study 16 beagle dogs implanted with adult heartworms d. When it comes to protecting your best friend against heartworm disease proheart 6 moxidectin makes it simple.

The injection site that resolved spontaneously within 24 hours of administration. The product label for proheart 12 cites an alarmingly long list of adverse events of proheart 6. Moxidectin is also available in combination products as with advantage multi. Cydectin injectable is specially formulated to allow moxidectin to be absorbed from the site of injection and distributed internally to the areas of the body affected by endo and or ectoparasitism.

It has recently been made available as a 10 percent moxidectin injection in 20 ml vials. Moxidectin is an endectocide in the milbemycin chemical class which shares the distinctive mode of action characteristic of macrocyclic lactones. The safety of proheart 12 ph 12. This is a topical solution product to be applied on the skin every month.